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  3. FCEN - Facultad de Ciencias Exactas y Naturales. UBA
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dc.provenanceFacultad de Ciencias Exactas y Naturales de la UBA-
dc.contributorNtalli, N.G.-
dc.contributorCottiglia, F.-
dc.contributor<div class="autor_fcen" id="1213">Bueno, C.A.</div>-
dc.contributor<div class="autor_fcen" id="127">Alché, L.E.</div>-
dc.contributorLeonti, M.-
dc.contributorVargiu, S.-
dc.contributorBifulco, E.-
dc.contributorMenkissoglu-Spiroudi, U.-
dc.contributorCaboni, P.-
dc.creatorNtalli, N.G.-
dc.creatorCottiglia, F.-
dc.creator<div class="autor_fcen" id="1213">Bueno, C.A.</div>-
dc.creator<div class="autor_fcen" id="127">Alché, L.E.</div>-
dc.creatorLeonti, M.-
dc.creatorVargiu, S.-
dc.creatorBifulco, E.-
dc.creatorMenkissoglu-Spiroudi, U.-
dc.creatorCaboni, P.-
dc.date.accessioned2018-05-04T22:08:04Z-
dc.date.accessioned2018-05-28T15:48:44Z-
dc.date.available2018-05-04T22:08:04Z-
dc.date.available2018-05-28T15:48:44Z-
dc.date.issued2010-
dc.identifier.urihttp://10.0.0.11:8080/jspui/handle/bnmm/68547-
dc.descriptionThe phytochemical investigation of the dichloromethane-soluble part of the methanol extract obtained from the fruits of Melia azedarach afforded one new tirucallanetype triterpene, 3-α-tigloylmelianol (1) and three known tirucallanes, melianone (2), 21-β-acetoxy-melianone (3), and methyl kulonate (4). The structure of the isolated compounds was mainly determined by 1D and 2D NMR experiments as well as HPLC-Q-TOF mass spectrometry. The cytotoxicity of the isolated compounds toward the human lung adenocarcinoma epithelial cell line A549 was determined, while no activity was observed against the phytonematode Meloidogyne incognita. © 2010 by the authors.-
dc.descriptionFil:Bueno, C.A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina.-
dc.descriptionFil:Alché, L.E. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina.-
dc.formatapplication/pdf-
dc.languageeng-
dc.rightsinfo:eu-repo/semantics/openAccess-
dc.rightshttp://creativecommons.org/licenses/by/2.5/ar-
dc.sourceMolecules 2010;15(9):5866-5877-
dc.source.urihttp://digital.bl.fcen.uba.ar/Download/paper/paper_14203049_v15_n9_p5866_Ntalli.pdf-
dc.subject21-β-Acetoxy- melianone-
dc.subject3-α-Tigloylmelianol-
dc.subjectCytotoxicity-
dc.subjectMelianone-
dc.subjectMethyl kulonate-
dc.subjectcytotoxin-
dc.subjectplant extract-
dc.subjecttirucallane-
dc.subjecttriterpene-
dc.subjectadenocarcinoma-
dc.subjectanimal-
dc.subjectarticle-
dc.subjectchemical structure-
dc.subjectchemistry-
dc.subjectdrug effect-
dc.subjectepithelium cell-
dc.subjectfruit-
dc.subjecthuman-
dc.subjectisolation and purification-
dc.subjectlung tumor-
dc.subjectMelia azedarach-
dc.subjectnematode-
dc.subjectpathology-
dc.subjecttumor cell line-
dc.subjectAdenocarcinoma-
dc.subjectAnimals-
dc.subjectCell Line, Tumor-
dc.subjectCytotoxins-
dc.subjectEpithelial Cells-
dc.subjectFruit-
dc.subjectHumans-
dc.subjectLung Neoplasms-
dc.subjectMelia azedarach-
dc.subjectMolecular Structure-
dc.subjectPlant Extracts-
dc.subjectTriterpenes-
dc.subjectTylenchoidea-
dc.titleCytotoxic tirucallane triterpenoids from Melia azedarach fruits-
dc.typeinfo:eu-repo/semantics/article-
dc.typeinfo:ar-repo/semantics/artículo-
dc.typeinfo:eu-repo/semantics/publishedVersion-
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